Objectives To examine the use of face mask intervention in mitigating the risk of spreading respiratory infections and whether the effect of face mask intervention differs in different exposure settings and age groups. Design Systematic review and meta-analysis. We evaluated the risk of bias using the Cochrane Risk of Bias 2 tool (ROB2). https://www.roneverhart.com/NeOn-Zero-Lefty-M390-BLADE-TITANIUM-HANDLE-MRBS-p11472/