Tumor Susceptibility Gene-101 (TSG101) promotes the endocytic degradation of transmembrane proteins and is implicated as a mutational target in cancer. yet the effect of TSG101 loss on cell proliferation in vertebrates is uncertain. By contrast. Drosophila epithelial tissues lacking the TSG101 ortholog erupted (ept) develop as enlarged undifferentiated tumors. https://themightyhobbyers.shop/product-category/sticker/
Genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor.
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